Posts Tagged ‘early detection’
January 16, 2013
During our annual Ladies’ Luncheon “You’ve Got a Date with the Valley Girl” on February 8th, Jesse Draper, Don Listwin and Sam Gambhir will focus their conversation on microbubble imaging technology. Sound complicated? Watch this short video where Don explains microbubble technology and how it could radically change the way we detect cancer and stop it at the earliest possible stage. We hope you’ll be able to join us!
January 15, 2013
Every year, Canary Foundation hosts a Ladies’ Luncheon, where we discuss our most cutting edge research on cancer early detection, and discuss its implementation. This year, our luncheon “You’ve Got a Date with the Valley Girl,” will be on February 8th, and will be hosted by Jesse Draper, creator and host of “The Valley Girl Show” where she interviews start up executives and innovators. She runs the technology blog Lalawag.com and is a regular featured writer for the Mashable, San Francisco Chronicle, Huffington Post and Glam.
Save the date and plan to sit in as Jesse interviews Sanjiv (Sam) Gambhir, MD, PhD, Chair of Radiology at Stanford University, Director of the Canary Center at Stanford and Don Listwin, Founder and Chairman of the Canary Foundation.
Check out the video below to see Don invite you to join us for this fabulous annual luncheon!
December 13, 2012
We’re so grateful for all of the contributions by scientists, donors, and everyone who participated in the work of cancer early detection in 2012! We sincerely thank our donors, volunteers, scientists, and clinicians for their hard work and support- we couldn’t do it without you! Watch the slideshow below for a look back at all of Canary’s successes and milestones in 2012.
December 5, 2012
Early cancer detection results of Canary Foundation led to the honor of being named Charity of the Week by The Week magazine. Canary Foundation early cancer detection research focuses on lung, prostate, pancreatic, breast and ovarian early detection methodologies. The Week magazine is a domestic and international magazine discussing the latest developments in business, health, science, technology, the arts, culture, consumer products and travel.
“Canary Foundation is the world’s first nonprofit dedicated entirely to the development of testes for early cancer detection. Founded in 2004 by Don Listwin, a successful technology executive who lost his mother to misdiagnosed ovarian cancer, Canary Foundation funds collaborative research by teams of cancer experts, with the aim of one day being able to identify early-stage cancer through a simple blood test.
The vast majority of cancer research funding goes to treatments of the disease in later stages; less than 15 percent currently goes to early-detection efforts, when cancer is at its most treatable. Canary Foundation is currently funding early-stage tests for lung, ovarian, pancreatic, prostate, and breast cancers.”
Thank you so much to The Week Magazine for featuring Canary Foundation as a charity to watch!
November 20, 2012
In keeping with Canary Foundation’s two-step process, the Canary Early Cancer Detection for Lung Cancer program’s goal is to develop a combined blood test and imaging approach to detect lethal lung cancer early, because early detection and treatment greatly enhance survival. The Canary Lung team is tackling the under-recognized area of lung cancer in non-smokers, seeking to understand why it develops and what the disease characteristics are in order to create screening tools for that disease.
Imaging for Lung Cancer Early Detection
CT screening* can reduce mortality from lung cancer, shown recently with the results of the National Lung Screening Trial, or NLST. Currently, when patients undergo a CT scan, it’s possible to see a problem spot, such as a lung nodule, but difficult to determine whether or not it is cancer. This presents a real opportunity to enhance the specificity of current imaging technology so it will be possible to determine if a spot isn’t or is cancer, and if so, whether it shows lethal characteristics.
Preliminary tests to improve the CT scan through molecular imaging have been very promising. A novel modified scan developed by Canary team members at Stanford uses new technologies to light up tumors so that their mass, and areas where they have spread, are clearly distinguishable in lung cancer patients. The technology will be tested for its specificity for early lung cancer (vs. benign conditions, such as scar tissue) in patients with lung nodules.
Biomarkers for Lung Cancer Early Detection
A blood biomarker test, used in combination with imaging, may also provide the specificity needed for accurate lung cancer screening. In line with Canary’s innovative and collaborative model, the Canary lung team has worked closely with five other organizations on a project to develop lung cancer biomarkers funded jointly by the National Cancer Institute (NCI). The most promising biomarkers from a comparison study in Vancouver are being selected.
The next step is to conduct a validation study of these biomarkers on carefully collected samples from the PLCO (Prostate, Lung, Colorectal, Ovarian) Screening Trial, a large randomized trial designed and sponsored by the NCI, to determine the effects of screening on cancer-related mortality.
If these biomarkers perform well on the PLCO samples, they will proceed through progressively more rigorous validation studies. Ultimately, blood biomarkers will be tested in combination with imaging in people currently getting screened for lung cancer, to validate the best approach for detecting lung cancer early and potentially saving lives.
*A computed tomography (CT) scan uses X-rays to make detailed pictures of structures inside the body.
November 6, 2012
On September 29, 500 riders convened at VMware in Palo Alto to set off on the Canary Challenge ride. All together, we raised $514,000 to benefit the Stanford Cancer Institute and the Canary Center at Stanford. This year’s numbers far surpassed last year’s ride of 344 riders and $300,000 raised. Take note: we have even bigger plans for next year!
Join us on Septeber 28, 2013 for the Canary Challenge 2013. In 2013, we’re looking forward to bringing 1,000 riders in to raise $1M and we’ve added a fun family 5K route for cyclists of all ages.
October 25, 2012
Dr. Mark Stolowitz, Director of the Proteomics Core Facility, tells us about Mass Spectrometers and how they’re used for cancer early detection research.
October 24, 2012
Currently, a woman living in the U.S. has a 12.1% risk of being diagnosed with breast cancer — that’s 1 out of 8 women. Think about 8 women you know; mothers, sisters, friends, coworkers – that’s how close this disease is to each of us. It’s a disease that requires our attention, resources, and brightest minds to work collaboratively to beat it. Earlier this year, we announced another bold step in our mission: the launch of the Canary Breast Cancer Program.
Currently, Canary funds two forward-thinking research projects that will lay the foundation for a new Breast Cancer Early Detection Initiative. One study will focus on finding biomarkers in the blood of women diagnosed with breast cancer that may indicate the presence of tumor growth. The second study will develop an imaging modality to detect breast cancer at the earliest stages. As such, it offers great potential in detecting very small tumors– pinpointing the location for surgery or target therapies before the cancer has the chance to spread. More »
September 18, 2012
Co- authored by Abbie Lieberman.
Imagine the year is 2030. Jane Doe has been feeling under the weather and is experiencing unfamiliar stomach pain. Her doctor sends her a portable, at-home screening kit that can test for multiple conditions including a variety of cancers. She takes a picture of the results using her smart device and sends them off to her doctor. A day later in the clinic, her doctor informs her that she has the earliest stages of ovarian cancer detectable. In this future time, Jane’s cancer cells are removed quickly and she is out of danger. In such a world, cancer is found early and is eliminated or reduced to a chronic illness, rarely being a fatal disease. Jane is closely monitored from this time forward and she goes on to live a long and happy life.
When cancer early detection tools become a reality, cancer screenings will change drastically and so will the impact of this disease on human life. Cancer could be re-categorized to become a condition or a disease swiftly dealt with, with fewer side effects or damage to the body. However, at-home tests to detect cancer early could be a long way off in the future. Is there something we can believe in without waiting for the Jane Doe scenario to come about?
In the more near-term, Canary researchers foresee important steps becoming practiced in our lifetime. A patient will most likely go into a doctor’s office, and get an extensive panel of blood work done at an annual exam. If the results are positive, an imaging test will be conducted to determine exactly where the cancer cells are. We already know this truth: when found early, a tumor can be removed or treated before it spreads. The patient’s survival rate increases to 90% (generalized) compared to the 10% survival rate when found late (today’s norm). More »
September 6, 2012
Nicole Urban, Ovarian Cancer Team Co-leader at the Canary Center and investigator at the Fred Hutchinson Cancer Research Center, provides viewers with an overview and the goals for Canary’s Ovarian Cancer Research Program. She also explains how working on collaborative research initiatives with Canary Foundation helps push her research to the next level.