Canary Researchers identify a recurrent fusion transcript that could provide a molecular marker for detection of ovarian cancer.
October 15, 2011
Most ovarian cancer deaths are caused by tumors of the serous histological type, which is rarely diagnosed before it has spread. By deep paired-end sequencing of mRNA from serous ovarian cancers, followed by deep sequencing of the corresponding genomic region, Drs. Brad Nelson, Charles Drescher, Patrick Brown, and others identified a recurrent fusion transcript.