Donate
Stopping Cancer Early – The Best Possible Investment

Blog

Archive for the ‘Cancer Early Detection Funding’ Category

Early Cancer Detection Initiative joins Canary Foundation Flock

October 24, 2017

University of Calgary cancer researchers to collaborate with top funding group

The Canary Foundation is now backing research at the University of Calgary. From left: Jon Meddings, dean of the Cumming School of Medicine; Elizabeth Cannon, president and vice-chancellor of the University of Calgary; Don Listwin, founder and CEO of the Canary Foundation; Tina Rinker, lead, Early Cancer Detection Initiative; Bill Rosehart, dean of the Schulich School of Engineering. Photo by Pauline Zulueta

When you learn Don Listwin has an engineering degree, it all makes perfect sense.

The man who started the Canary Foundation, the world’s leading non-profit funding agency for early-detection cancer research, is looking to defeat the disease the way an engineer would. His strategy: prevent the problem before it starts, rather than trying to fix it after disaster has struck.

“Early detection of cancer means confronting the disease when it is most treatable and chances for full recovery are greatest,” explains Listwin, founder and chairman of the Canary Foundation, and an electrical engineering graduate. “By focusing our efforts on research dealing with early detection and pre-emptive testing, we are finding and fighting cancer when it is most vulnerable and easiest to defeat.”

This week, the Early Cancer Detection Initiative at the University of Calgary officially joins the esteemed list of research programs backed by the Canary Foundation. Since 2004, the foundation has helped fund a select group of collaborative laboratories, starting with the Fred Hutchinson Cancer Research Center in Seattle. The University of Calgary joins the Canary Center at Stanford; the MD Anderson Cancer Center, Houston, Texas; Cancer Research U.K.; and OHSU Knight Cancer Institute in Portland, Ore. on the short list of Canary Foundation collaborators.

For Listwin, cancer is a very personal adversary. Having lost his mother to misdiagnosed late-stage ovarian cancer and watched his father fight colon cancer, the Canadian technology mogul decided to do something about it.

Having previously climbed to the near-pinnacle of his chosen industry — Listwin was CEO of Openwave Systems and had been the number two executive at Cisco Systems — he took on cancer with the same drive and determination, launching the Canary Foundation.

Listwin says early-detection research like that taking place at UCalgary is key to ensuring victims become survivors. “The work taking place here in Calgary on diagnostic tools that will allow for early detection of high-mortality, treatment-resistant cancers is vital to our goal,” he says. “We are proud and enthused to be supporting the University of Calgary’s Early Cancer Detection Initiative.”

A partnership established by the Arnie Charbonneau Cancer Institute between the Schulich School of Engineering, the Cumming School of Medicine, and the Tom Baker Cancer Centre, the pan-university Early Cancer Detection Initiative’s mission is three-fold. Namely to develop strategies and methods for non-invasive earlier detection of cancer, discover better ways to predict the behaviour of individual cancers, and accelerate the development of new commercially viable cancer detection tests and technologies.

Led by bioengineering professor Kristina Rinker, PhD, the Early Cancer Detection Initiative team, including medical oncologist Dr. Don Morris and surgical oncologist Dr. Oliver Bathe of the Charbonneau Cancer Institute and the Department of Oncology, aims to engage with researchers across campus.

The goal is to advance cancer detection technology development through providing funding opportunities, fostering interdisciplinary collaborations, and building connections to local and international mentors, researchers, and resources. Researchers are currently investigating new ways of detecting those at risk of developing cancer, through blood tests for detecting early disease, body fluid analysis, and technologies to detect metastatic cancer, among other key projects.

Rinker is director of the Centre for Bioengineering Research and Education, and associate professor of Chemical and Petroleum Engineering at the Schulich School of Engineering, associate professor in the Department of Physiology and Pharmacology at the CSM and member of the Charbonneau Cancer Institute. She says the Canary Foundation’s support is a significant boost to the research taking place in Calgary, and it places the university in a position to work and collaborate with the world’s best.

“We are very excited to join the dedicated international team of researchers in the Canary network to detect cancer earlier and open doors to stopping or even reversing cancer progression,” explains Rinker.

The University of Calgary’s multidisciplinary Engineering Solutions for Health: Biomedical Engineering research strategy is focused on developing solutions for pressing health challenges in disease and injury prevention, diagnosis and treatments. Researchers are applying systems engineering principles to continuously improve the health system.

This article by Michael Platt originally appeared on the University of Calgary website (www.ucalgary.ca).

Cycling for Canary – one rider’s drive

June 13, 2016

Nitish Amin is a 3-time Canary Challenge participant and is currently gearing up for his fourth Challenge, riding with team Cisco. In this guest blog he reflects on his love of biking and passion for supporting cancer early detection.

Growing up in India, I biked everywhere, every day, as a child.

I grew up, as we all do, moved to the United States and set biking aside. However, three years ago, I started biking again.

Nitish3-768x457The first time I got on my Cannonade (that’s a really great bike, if you don’t know) something just felt right. I have that feeling when I get on the saddle every Sunday morning.

I see more when I’m on my bike than when I’m in a car. I usually take the roads and routes that I haven’t explored. It is an amazing hobby that allows me to slow down, even when I’m going 20+ miles per hour. I stop to talk to people. For the next few hours that I’m on my bike, it’s just me, nature, and my fellow biking enthusiasts. I am always amazed at how new many friends I make see when I’m riding. These friends I made, we call ourselves, “CRANK OF DAWN” because we like to ride early.

It’s the same during my 8+ years at Cisco, where I get to see how many great people I work with. I am a Software Technology Manager and while we’re all moving fast to innovate and to change the world, when we take a moment to slow down, enjoy what we do, we get to see a little more, take a few unexplored paths, and just talk to each other. We also have time to give back together.

I learned about the Canary Foundation through Cisco’s volunteer program. It is the non-profit organization dedicated solely to the funding, discovery and development of tests for early cancer detection. This photo of me is during a 50-mile ride for the Canary Challenge. I like that Cisco encourages us to give back in ways that are personal to us, and in our local communities.

My father started one of the first early cancer detection centers back in the 1970s in Gujarat, India. When I ride for Canary, I feel that sense of connection between where I am now, at Cisco, and where I came from, all while contributing to a worthy cause.

Canary Summit Brings Early Cancer Detection Researchers Together

May 10, 2016

mayerPhoto_212More than 100 members of Stanford University’s scientific community met Tuesday, May 4 at the University Club in Palo Alto. Although their backgrounds were different, they had one major thing in common: cancer early detection. The event – the first ever Canary Summit – allowed researchers to share their work in that field, which ranged from innovative early detection using molecular imaging and cancer biomarkers, to the development of new technologies and medical devices for detecting cancer in its most early stages.

mayerPhoto_187

All those present were faculty and associates of the Canary Center at Stanford, a world-class facility dedicated to cancer early detection research programs. The Canary Foundation was instrumental in establishing the center and continues to fund it significantly.

At the Summit, the Canary Foundation awarded a $50,000 seed grant and committed to awarding $200,000 more in seed grants for attendees of the event to fund their research.

mayerPhoto_202

Scientists were encouraged to create posters that illustrated the focus and findings of their early detection research, and attendees voted on the best posters.

Top poster winners were:

  • First Place: Intravascular magnetic enrichment of circulating tumor cells. Jessie Ge (presenting author). Authors: Tianjia J. Ge, Amin Aalipour, Ophir Vermesh and Sanjiv S. Gambhir.

  • Second Place: NFIB is a novel metastasis-specific biomarker of small cell lung cancer. Jessika Baral (presenting author). Authors: Jessika Baral, Dian Yang and Julien Sage.

  • Third Place: Label-free Magnetophoretic Isolation of Circulating Tumor Cells and Clusters from Blood. Jaeyoung Yang (presenting author). Authors: Jaeyoung Yang, N. Gozde Durmus, Hojae Lee, Baris D. Ercal, Ozlem Ercal, Huiping Zhang, Christian Hoerner, Alice C. Fan, Juergen K. Willmann, Ronald W. Davis, Lars Steinmetz and Utkan Demirci.

For more photos of the Canary Summit, visit our album on Facebook.

Longtime Canary Supporters Will Match Your Gift for Silicon Valley Gives May 3

April 28, 2016

Evan and Cindy Goldberg of Woodside, CA will match your gift to fund early cancer detection research up to $100,000 for Silicon Valley Gives on May 3. If you make a donation to Canary Foundation during this 24-hour online fundraising event, it will be matched by the Goldbergs’ generous donation.

To contribute, visit Canary Foundation’s Silicon Valley Gives fundraising page anytime on Tuesday, May 3.

Goldbergs

Evan and Cindy Goldberg

Why the Goldbergs support early detection research 

There’s no debate that early cancer detection saves lives. No one knows this better than the Goldbergs.

The couple has several family members who have had cancer, but thanks in large part to early diagnosis, all of them survived.

“They were helped by early detection, and it was a major factor in being cured. Even earlier detection may have made their treatments less invasive,” Cindy says.

Longtime supporters of Canary Foundation, the Goldbergs believe that finding cancer earlier, with more accurate testing methods, is the first line of defense, and that reliable earlier detection will make new cancer therapies more effective.

“We are inspired by the incredible commitment of Don Listwin, Canary’s founder, and Dr. Sanjiv Gambhir, chair of Radiology at Stanford University and director of the Canary Center at Stanford,” shares Evan. “Their ideas are life-saving, cost-effective and long overdue.”

Join Evan and Cindy in helping Canary Foundation find cancer early. It’s about time.

Our Newest Faculty Member Arrives from Harvard: Dr. Utkan Demirci – A Microfluidic Technology Platform

March 6, 2014

To implement new discoveries in the clinic, we are committed to developing novel micro- and nanoscale bioengineering and biomedical microfluidic technology platforms to enable clinical diagnostics and point-of-care tests. To achieve this goal, we have recently recruited Dr. Utkan Demirci from Harvard Medical School to lead our technology development efforts. Dr. Demirci’s previous efforts have yielded a point-of-care microchip technology to detect ovarian cancer biomarkers (e.g., HE4) using a 10-minute microchip assay and a cell phone as the detector.

Screen Shot 2014-03-18 at 10.36.05 AM

Dr. Demirci will continue to innovate around point-of-care diagnostics, microfluidics assays and the development of technology platforms at the convergence of engineering, biology and materials science. Dr. Demirci brings his 15-person lab from Harvard this spring.

Further details of his research can be found here.  The movie below, from BAMM Labs (Bio Acoustic Mems in Medicine) gives the general idea of his point-of-care diagnostic technology although it’s for a different medical application.

Registration Open for Canary Challenge 2014 in Honor of World Cancer Day

February 4, 2014

In honor of World Cancer Day, we are officially opening registration for the Canary Challenge 2014. Register for the ride now for $25 until March 31.

World Cancer Day is a chance to raise our collective voices in the name of improving general knowledge around cancer and dismissing misconceptions about the disease. For Canary, we’re emphasizing the need for more cancer early detection research, awareness, and advocacy. A great way to get involved is by participating in the Canary Challenge 2014.

This amazing one-day cycling event is about to get bigger and better than ever. The event will be hosted at HP’s campus in Palo Alto on Hanover St. We’re aiming high this year with a goal of raising $1.5 million, recruiting 150 teams and over 1,500 riders. This year’s ride will benefit the Canary Center at Stanford, supporting the researchers, scientists and doctors who are dedicated to cancer early detection. Register now and be part of the pioneering edge of cancer early detection research!

Upwards and Onwards: Canary Goals for 2014

January 29, 2014

The beginning of the year presents a cue to reflect on the successes of the previous year, and look forward to goals for the coming months. We’re delighted to announce progress with our research that has tremendous implications for future innovations, as well as our ambitions for the Canary Challenge 2014.

slide

New technologies always evoke excitement and anticipation. Here at Canary, if a scientist wants to use a new technology to advance or improve the ways we detect cancer tumors early, we are all for it. Enhanced ultrasound using microbubble technology is one of these technologies.

This technology will change the way doctors view tumors. Microbubbles are miniature gas bubbles, mostly containing oxygen or air, which can be uniformly suspended in a liquid such as blood. Due to their size, they can pass through even the smallest of blood vessels and therefore are commonly used together with medical ultrasound imaging. As effective vehicles for highlighting blood in ultrasound images, Canary scientists use microbubbles as a contrast agent to view cancer tumors. Our clinical trials in Rome with women who have ovarian cancer have produced great results. Here in the US, we anticipate replicating microbubble technology for applications with breast cancer, prostate and pancreatic cancer.

We also value and actively seek out key partnerships, whether academic or industry. Soon we’ll announce a partnership with Genomic Health Inc. in the area of prostate cancer. We’re in talks with MD Anderson in Houston to help with coordinating a national multi-institutional lung cancer study.

We have great plans for our largest fundraising event, the Canary Challenge, which is about to get bigger and better than ever. Mark your calendar now for September 27, 2014. Register now for $25 until March 31. The event will be hosted at HP’s campus in Palo Alto on Hanover St. We’re aiming high this year with a goal of raising $1.5 million, recruiting 150 teams and over 1,500 riders. This year’s ride will benefit the Canary Center at Stanford, supporting the researchers, scientists and doctors who are dedicated to cancer early detection. Come be a part of an amazing one-day cycling event!

We’re pleased to announce that we will again be partnering with women’s pro cycling team extraordinaire, the Vanderkittens, who will host monthly training rides for Canary Challenge riders. Hani Juha, a cyclist and great coach, of Menlo Bike Club will also offer weekly training rides, an annual training program, as well as monthly clinics. We invite anyone and everyone in the Canary community to take advantage of these tailored experiences to brush up on their skills in time for the event.

What are your hopes and dreams for cancer early detection research at Canary Foundation? Let us know in the comments below!

What’s it Like to Ride the Canary Challenge?

December 16, 2013

Save the date to register for the Canary Challenge 2014- registration opens on January 4 in the New Year!

 

Canary Highpoints: Cancer Early Detection Research Progress 2013

December 4, 2013

Canary Foundation’s progress continues to be on a rapid path. Through prestigious partnerships, research, and clinical trials with quantifiable results, Canary Foundation is funding early detection research that will save lives and permanently change the landscape of cancer diagnostics. People like you have made this progress possible.

In 2013, our partnership with Stanford University expanded and we moved into our new state-of-the-art Canary Center at Stanford to continue our work realizing early detection solutions.

We are pleased to share a new video featuring our high points. We thought this was a great way to reflect on key ideas Canary was founded upon that have become reality. We invite you to view our 5-minute Canary Foundation video!

When you and your family make giving decisions this holiday, we ask that make cancer early detection a priority. Please give generously.

Prostate Cancer Early Detection: Canary PASS Trial Hits Important Milestone

November 14, 2013

About one man in six will be diagnosed with prostate cancer in his lifetime. Most men diagnosed with prostate cancer will not die from it. With screening, we’re doing better at identifying prostate cancer early. But now, the clinical question is: with a prostate cancer diagnosis, do we treat, or is treatment not necessary?

ProstateTreating prostate cancer when it’s not necessary exposes men to potential side effects—including incontinence and impotence– of aggressive treatment like surgery. This is known as overtreatment. We need better tools to differentiate aggressive prostate cancer from non-aggressive prostate cancer to guide these decisions.

In 2007, the Canary prostate team decided to focus on this important clinical question. How will we distinguish lethal from non-lethal prostate cancer? Identifying the difference early on will save lives. New tools will also help end unnecessary biopsies and overtreatment.

By 2008, the team launched a clinical trial called PASS, the Prostate Active Surveillance Study. Men with early stage, localized, low-risk prostate cancer can enroll and have their cancer closely monitored for signs of progression. This process is called active surveillance. The trial’s goal is to manage low-risk prostate cancer through active surveillance while identifying markers to distinguish non-aggressive prostate cancer from potentially lethal disease.

The PASS trial has been running smoothly, and in October 2013, the PASS Trial reached another major milestone when the 1,000th man was enrolled in the trial.

We are so grateful for Canary Foundation supporters, who provided funding early on for this work. They recognized that the project was underfunded and important. We’re also extremely thankful to the men who participated in the trial for contributing tens of thousands of samples to prostate cancer early detection research. Thank you!