Archive for the ‘early detection prostate cancer’ Category
Canary funds four collaborative studies that pair faculty at Stanford with faculty at the University of Cambridge
February 15, 2018
Canary Foundation was ahead of the cancer early detection wave when it started in 2004. Since then, academic institutions, such as the University of Cambridge in the UK and the University of Calgary in Canada, have looked to Canary for advice as they build out their own cancer early detection programs.
This year, one such collaboration is taking shape in dynamic ways. Canary’s partnership with the University of Cambridge has resulted in four promising studies that partner researchers from Cambridge with researchers from Stanford. These projects, jointly funded by Canary Foundation and the Cancer Research UK Cambridge Centre, will explore innovative ways to detect prostate, lung, esophageal and renal cancers at an early stage.
In order to receive seed grants for these projects, applications had to include faculty at both Stanford and Cambridge. By fostering this transatlantic collaboration, Canary hopes to bring outstanding academic and clinical researchers from the US and UK together to tackle some of the most challenging questions in detecting cancer sooner.
The awards were announced at Cambridge’s third annual early detection symposium on January 15. You can read more about these collaborations below or by watching the video.
“A multi-modal approach to discover novel blood-based biomarkers for early detection of poor prognosis prostate cancer”
Tanya Stoyanova, an assistant professor of radiology at the Canary Center, is partnering with Vincent Gnanpragasam, an urologist at Cambridge University Hospitals, to identify different types of tumors in men with prostate cancer. The goal is to distinguish between aggressive tumors that would require immediate treatment, and slow-growing tumors that may not need treatment immediately but could be monitored closely so that any changes in the tumor can be picked up and acted upon. Their project will use data from a number of sources including tumor DNA found circulating in the blood, protein molecules found in cancer cells, and MRI imaging of the tumor.
“Early cancer detection through transcriptomic analysis of host immune cells”
Tom Soh, a professor of radiology at the Canary Center, is exploring new ways to detect early-stage lung cancer through his partnership with Robert Rintoul, a thoracic consultant at Cambridge University Hospitals. The pair is studying the immune cells in blood samples to see if there are particular signals that could be used to identify lung cancer early.
“Levitating a sponge for the early detection of Esophageal Adenocarcinoma”
Utkan Demirci, a professor of radiology at the Canary Center, is working with Rebecca Fitzgerald, Cambridge’s early detection program co-lead, to detect early signs of esophageal cancer. They will use a new nanotechnology developed by Demirci that separates different types of cells using a magnetic field. The technology will be applied to the mixture of cells collected from patients that are given a Cytosponge test developed by Fitzgerald that can diagnose Barrett’s esophagus – a common condition that, in some cases, develops into esophageal cancer.
“Early detection of renal cell carcinoma using DNA methylation markers in urine”
Olivier Gevaert, an assistant professor of medicine and of biomedical data science at Stanford, and John Leppert, an associate professor of urology at Stanford, are teaming up with Charlie Massie, a group leader in Cambridge’s early detection program. They will study whether it is possible to detect the early stages of a type of kidney cancer (Renal Cell Carcinoma) using biomarkers found in urine. Their research will look at specific signals in the DNA cells called methylation.
January 29, 2014
The beginning of the year presents a cue to reflect on the successes of the previous year, and look forward to goals for the coming months. We’re delighted to announce progress with our research that has tremendous implications for future innovations, as well as our ambitions for the Canary Challenge 2014.
New technologies always evoke excitement and anticipation. Here at Canary, if a scientist wants to use a new technology to advance or improve the ways we detect cancer tumors early, we are all for it. Enhanced ultrasound using microbubble technology is one of these technologies.
This technology will change the way doctors view tumors. Microbubbles are miniature gas bubbles, mostly containing oxygen or air, which can be uniformly suspended in a liquid such as blood. Due to their size, they can pass through even the smallest of blood vessels and therefore are commonly used together with medical ultrasound imaging. As effective vehicles for highlighting blood in ultrasound images, Canary scientists use microbubbles as a contrast agent to view cancer tumors. Our clinical trials in Rome with women who have ovarian cancer have produced great results. Here in the US, we anticipate replicating microbubble technology for applications with breast cancer, prostate and pancreatic cancer.
We also value and actively seek out key partnerships, whether academic or industry. Soon we’ll announce a partnership with Genomic Health Inc. in the area of prostate cancer. We’re in talks with MD Anderson in Houston to help with coordinating a national multi-institutional lung cancer study.
We have great plans for our largest fundraising event, the Canary Challenge, which is about to get bigger and better than ever. Mark your calendar now for September 27, 2014. Register now for $25 until March 31. The event will be hosted at HP’s campus in Palo Alto on Hanover St. We’re aiming high this year with a goal of raising $1.5 million, recruiting 150 teams and over 1,500 riders. This year’s ride will benefit the Canary Center at Stanford, supporting the researchers, scientists and doctors who are dedicated to cancer early detection. Come be a part of an amazing one-day cycling event!
We’re pleased to announce that we will again be partnering with women’s pro cycling team extraordinaire, the Vanderkittens, who will host monthly training rides for Canary Challenge riders. Hani Juha, a cyclist and great coach, of Menlo Bike Club will also offer weekly training rides, an annual training program, as well as monthly clinics. We invite anyone and everyone in the Canary community to take advantage of these tailored experiences to brush up on their skills in time for the event.
What are your hopes and dreams for cancer early detection research at Canary Foundation? Let us know in the comments below!
December 16, 2013
Save the date to register for the Canary Challenge 2014- registration opens on January 4 in the New Year!
October 29, 2013
Photo: The clinical trial coordinators for the Canary Prostate Active Surveillance Study (PASS) accept the 2013 Canary Award on behalf of the Canary Prostate Team.
Dr. Dianne Miller was presented with the award for her team’s success in promoting adoption of ovarian cancer prevention programs throughout the Canadian province of British Columbia. Because lethal ovarian cancer often originates in fallopian tubes, their removal can prevent the development of ovarian cancer, potentially reducing the incidence by 50% or more. Since the advent of the British Columbia educational campaign in September 2010, clinics across the province have seen a practice shift toward removal of fallopian tubes during common gynecological surgeries (such as hysterectomy and tubal ligation), thanks to the efforts of Dr. Miller’s team.
The Canary Prostate team was presented with the Canary Award for the team’s success in meeting or exceeding all of its major milestones in the Prostate Active Surveillance Study (PASS) clinical trial. Earlier in the month of October, 2013, the PASS trial celebrated reaching another major milestone, as the 1,000th participant was enrolled in the trial. The trial’s goal is to manage low-risk prostate cancer through active surveillance while identifying markers to distinguish non-aggressive prostate cancer from potentially lethal disease.
Congratulations to both teams for all their hard work, and to all the Canary teams who work tirelessly to develop research and solutions to make accessible cancer early detection a reality.
October 7, 2013
In the United States, it is estimated that there will be 232,340 new breast cancer cases and 39,620 breast cancer mortalities in 2013. 1 in 8 women will be diagnosed with breast cancer during their lifetime. Despite the widespread use of mammography, the technology is limited as many cancers are missed and conversely many women undergo biopsies and surgeries of benign or non-aggressive tumors.
Canary Foundation is supporting a Breast Cancer Early Detection Initiative focused on finding blood-based and imaging biomarkers to improve the current state of breast cancer early detection. The vision of the blood work is to distinguish women with benign versus malignant tumors, and to identify the aggressive, hard to detect, breast cancers. The vision of the imaging work is to detect breast cancer at the earliest stages, when the tumors are very small.
Canary is committed to funding safe, efficient, cost effective tests for cancer early detection.
October 3, 2013
This past weekend, 800 cyclists converged at VMware village to kick off Canary Challenge 2013, a great increase over the number of riders from last year! Over $800,000 was raised to benefit cancer research at the Stanford Cancer Institute and Canary Center for Cancer Early Detection at Stanford.
There were a total of 78 teams participating, with over 120 volunteers cheering, manning registration, and passing out drinks and snacks to replenish riders along the route. Most incredible was the great energy at the event – participants’ dedication and commitment to the cause was palpable, and the celebratory air when cyclists returned triumphant from their rides was electric.
We loved when riders stopped by the social photo booth to show us “#WhyIRideCanary”. Everyone who contributed to the event did so because they were inspired by the need for cancer early detection research. It was incredible to hear their stories – a great reminder of why we ride.
A great thank you to all the riders, sponsors, volunteers and staff who came together on September 28 to make this ride such a great success. Ride on, Canary Challenge participants! Save the date for next year: September 27, 2014!
September 18, 2013
We’re currently 10 days away from the Canary Challenge, and weather reports show that conditions will be perfect the day of the ride. We are so excited to see all the riders, sponsors, and volunteers (and their families) at the Canary Challenge on the 28th!
Currently, we’re running a contest to get you excited about raising funds for cancer early detection and getting your friends signed up for the ride. The incentive? A pair of FABULOUS high end display goggles from Recon Instruments (UVEX Model G.GL9). These goggles give you all the information you could ever dream of wanting delivered instantly, hands free and direct to eye. It’s the world’s first heads up display for sports. Thanks to Recon Instruments for their generous donation!
This incredible prize will go to the first three cyclists who complete two tasks:
1: Raise at least $400 or more
2: Bring in ONE new cyclist who raises $400 or more
The deadline for this contest is Monday, September 23. To participate, complete the steps above and email Jesse to let him know you’re eligible for the prize.
Additionally, we’d like to call attention to the top five Canary Challenge fundraisers so far. These individuals have collectively raised more than $45,000 and they’re still going strong!
- Julie Kaufman ($11,667.00)
- Steve Ciesinski ($10,695.00)
- Don Listwin ($10,000.00)
- Stephen Rooks ($8,000.00)
- Patrick Gelsinger ($6,850.00)
Many thanks to these fundraisers for serving as such great inspiration to keep reaching for as many donations as possible to benefit cancer early detection research at the Stanford Cancer Institute and the Canary Center at Stanford. Way to go!
September 13, 2013
For Immediate Release
Contact: Erica Glessing
September 28, 2013 Event Draws Vanderkitten Pro Cyclists
Palo Alto, CA – The California cycling event Canary Challenge on Sept. 28 2013 in Palo Alto is experiencing a major growth spurt in registration over 2012 with registration up more than 60 percent. The event, produced by the Canary Foundation, benefits Stanford Cancer Institute and the Canary Center at Stanford for Cancer Early Detection. “We are thrilled with the surge in registration and sponsorships in 2013,” says Don Listwin, Canary Foundation chairman and founder of the Canary Challenge. “We built an outstanding series of routes that will challenge or entertain every level of cyclist, from the new 5K Canary Cruiser to the Century.”
More than 815 cyclists have registered to participate, an exciting 61 percent increase over 2012 registration. Many of the cyclists participate with a personal reason for riding. For instance, Carolyn Helmke of Mountain View, an accomplished individual fundraiser, is a cancer survivor. “I support the Canary Challenge 100 percent,” says Helmke, who encouraged her friends to give a donation to the Canary Challenge in lieu of birthday gifts this year. She has raised over $4,000 to date, just one of the hundreds of participants who are on track to collectively raise $1 million in donations for cancer research this year. Cancer early detection research is a cornerstone of Canary Foundation.
Pros from the Vanderkitten Racing team are among those to support Canary Challenge in a big way, with more than six of the professional women cyclists on board to fundraise and ride on September 28. “Funds raised by the Canary Challenge go directly to early cancer detection research, and this makes the event a perfect fit for Vanderkitten Racing,” says Dave Verrecchia,Vanderkitten team owner. More »
September 11, 2013
In this latest installment of our Canary Minute series, Sasha Hao interviews Canary Challenge participants taking part in the last Vanderkitten last training ride before the Canary Challenge, the premier Palo Alto CA cycling event held each September to raise funds for cancer early detection and the Stanford Cancer Institute. This video gives an inside look into the Vanderkitten training ride and all the different reasons why the riders are passionate about the Canary Challenge.
Check out our entire Canary Minute playlist on YouTube!
September 6, 2013
The countdown has begun! It’s less than two full weeks to the day of the Canary Challenge, and everyone is looking forward to the big day. Whether you’re going for the full century ride, or have your sights set on the 5k walk/run route, it’s essential to get ready and be prepared for what’s ahead. To make it easy, we’ve put together a short checklist to help guide you!
Part of participating in the Canary Challenge is fundraising to benefit cancer early detection research at Stanford Cancer Institute and the Canary Center at Stanford. Keep an eye on your fundraising progress and monitor how far you’ve come to reach your goals. If you’re struggling with the fundraising aspect of the Canary Challenge, take a look at our blog: How to Raise $400 in 5 Days.
Stay Healthy & Hydrate
One key to a good athletic performance is to treat your body right by eating healthy and hydrating. In the weeks and days leading up to the Canary Challenge, drink as much water as possible, while eating healthy, balanced meals. Your body will thank you during the ride!
Check Your Ride
Whether you ride your bike every day, or if you’re taking it out of the basement and dusting it off, it’s critical to make sure your bike is in working order. Check your tires and brakes so that you can have a smooth — and safe — ride on September 28. For the ultimate safety check, go to a bike shop, like Mike’s Bikes, one of our sponsors, and ask for a check-up on your bike.
If you can, get more friends to register for the Canary Challenge! However, some of your friends, family and acquaintances might be more comfortable volunteering as opposed to riding. We’re actively looking for volunteers- if you know someone who’s interested in volunteering, have them register with us ASAP!
Make a Plan with Your Team Members
Many people who ride the Canary Challenge do so with a team, either organized around a company, a concept, or a person whose memory they’re honoring. Get in touch with your team members and communicate about timing, outfits, and other plans to meet up and ride together. Coordinating your team will help you build more great memories during the Canary Challenge.