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Archive for the ‘prostate cancer early detection’ Category
Early Cancer Detection Success Leads to Canary Featured as Charity of The Week
December 5, 2012
Early cancer detection results of Canary Foundation led to the honor of being named Charity of the Week by The Week magazine. Canary Foundation early cancer detection research focuses on lung, prostate, pancreatic, breast and ovarian early detection methodologies. The Week magazine is a domestic and international magazine discussing the latest developments in business, health, science, technology, the arts, culture, consumer products and travel.
“Canary Foundation is the world’s first nonprofit dedicated entirely to the development of testes for early cancer detection. Founded in 2004 by Don Listwin, a successful technology executive who lost his mother to misdiagnosed ovarian cancer, Canary Foundation funds collaborative research by teams of cancer experts, with the aim of one day being able to identify early-stage cancer through a simple blood test.
The vast majority of cancer research funding goes to treatments of the disease in later stages; less than 15 percent currently goes to early-detection efforts, when cancer is at its most treatable. Canary Foundation is currently funding early-stage tests for lung, ovarian, pancreatic, prostate, and breast cancers.”
Thank you so much to The Week Magazine for featuring Canary Foundation as a charity to watch!
Early Cancer Detection Update for National Cancer Institute and National Institute of Health
November 29, 2012
The National Cancer Institute, under the National Institute of Health, plays a crucial role in cancer research throughout the United States. As the nation’s “investment in cancer,” NCI has quite a bit of ground to cover. NCI’s annual budget is approximately $5 billion. In 2010, 7% of NCI’s budget was allocated to the Division of Cancer Prevention. The Early Detection Research Group is one of ten groups in this division, and the Early Detection Research Network (EDRN) is one of the division’s six major projects. This means that early detection research is receiving a fraction of that 7% budget.
Although early detection may not be their top focus, NCI has moved to make a more substantial investment in early detection research and technology, and is making headway in this area. Additionally, NCI has collaborated with Canary Foundation on early detection projects.
NCI started EDRN to bring together multiple institutions working on early detection research. Early detection has many facets and therefore requires the work of leaders from many fields. By working together, different institutions can more effectively facilitate advances in early detection science and translate these advances into clinical practice. Canary Foundation operates in this same way, organizing multi-institutional studies and moving studies towards clinical practice.
The NCI has also developed accelerated programs called SPORES, or Specialized Programs of Research Excellence. SPORE studies are set up to be short-term (five years or less) and high-impact where they can translate quickly to clinical use and improve the lives of humans. Their objective is to reduce cancer incidence and mortality, while seeking to better the quality of life for cancer patients. Several of Canary Foundation’s programs and researchers are involved in important SPORE work including our Ovarian and Prostate Cancer Programs. More »
Lung Cancer Early Detection Moves Forward at Canary Foundation
November 20, 2012
In keeping with Canary Foundation’s two-step process, the Canary Early Cancer Detection for Lung Cancer program’s goal is to develop a combined blood test and imaging approach to detect lethal lung cancer early, because early detection and treatment greatly enhance survival. The Canary Lung team is tackling the under-recognized area of lung cancer in non-smokers, seeking to understand why it develops and what the disease characteristics are in order to create screening tools for that disease.
Imaging for Lung Cancer Early Detection
CT screening* can reduce mortality from lung cancer, shown recently with the results of the National Lung Screening Trial, or NLST. Currently, when patients undergo a CT scan, it’s possible to see a problem spot, such as a lung nodule, but difficult to determine whether or not it is cancer. This presents a real opportunity to enhance the specificity of current imaging technology so it will be possible to determine if a spot isn’t or is cancer, and if so, whether it shows lethal characteristics.
Preliminary tests to improve the CT scan through molecular imaging have been very promising. A novel modified scan developed by Canary team members at Stanford uses new technologies to light up tumors so that their mass, and areas where they have spread, are clearly distinguishable in lung cancer patients. The technology will be tested for its specificity for early lung cancer (vs. benign conditions, such as scar tissue) in patients with lung nodules.
Biomarkers for Lung Cancer Early Detection
A blood biomarker test, used in combination with imaging, may also provide the specificity needed for accurate lung cancer screening. In line with Canary’s innovative and collaborative model, the Canary lung team has worked closely with five other organizations on a project to develop lung cancer biomarkers funded jointly by the National Cancer Institute (NCI). The most promising biomarkers from a comparison study in Vancouver are being selected.
The next step is to conduct a validation study of these biomarkers on carefully collected samples from the PLCO (Prostate, Lung, Colorectal, Ovarian) Screening Trial, a large randomized trial designed and sponsored by the NCI, to determine the effects of screening on cancer-related mortality.
If these biomarkers perform well on the PLCO samples, they will proceed through progressively more rigorous validation studies. Ultimately, blood biomarkers will be tested in combination with imaging in people currently getting screened for lung cancer, to validate the best approach for detecting lung cancer early and potentially saving lives.
*A computed tomography (CT) scan uses X-rays to make detailed pictures of structures inside the body.
Canary Challenge 2012: Ride for Life Raises Funds for Cancer Research
November 6, 2012
On September 29, 500 riders convened at VMware in Palo Alto to set off on the Canary Challenge ride. All together, we raised $514,000 to benefit the Stanford Cancer Institute and the Canary Center at Stanford. This year’s numbers far surpassed last year’s ride of 344 riders and $300,000 raised. Take note: we have even bigger plans for next year!
Join us on Septeber 28, 2013 for the Canary Challenge 2013. In 2013, we’re looking forward to bringing 1,000 riders in to raise $1M and we’ve added a fun family 5K route for cyclists of all ages.
Founders Expedite Change
October 30, 2012
Founders of nonprofit organizations are motivated to make a big difference where they see a problem in society. They come to understand there is a great need that only a nonprofit can fill. They allocate resources into starting the nonprofit and to developing a community that will help further the mission and resolve the problem. Canary Foundation was conceived by founder Don Listwin, who gives his all to generating affordable and easy early cancer detection biomarkers and imaging tools as part of Canary Foundation’s mission.
If you look at the history of philanthropy, you may be surprised to learn how far back this idea goes, and marvel at the rich environment of direct services, research, innovation, education, culture and arts the nonprofit sector has spawned. We can trace this idea as far back as Plato, the ancient Greek philosopher who donated his farm to his nephew upon his death in 347 A.D., to fund students and faculty in the Academy of Athens he founded. More »
Early Detection Tool Mass Spectrometers Explained by Dr. Mark Stolowitz
October 25, 2012
Dr. Mark Stolowitz, Director of the Proteomics Core Facility, tells us about Mass Spectrometers and how they’re used for cancer early detection research.
Success! Canary Challenge Roundup Raises Funds for Cancer Research, Early Cancer Detection
October 3, 2012
Here at Canary Foundation we’re celebrating the success of another exceptional Canary Challenge race! We had a great time, and judging from the smiles we saw, you did too.
Canary Foundation is the world’s first non-profit organization dedicated solely to the funding, discovery, and development of tests for early cancer detection. Canary Foundation is dedicated to delivering early detection tests for solid cancer tumors by 2015.
We are so thankful for all the sponsor companies and volunteers whose generous contributions made the day a success – we really couldn’t have done it without you.
In the meantime, here are a couple of shots from the race for those of us who weren’t able to join us. For a full photo gallery, check out the slideshow on the Canary Facebook Page.
Canary Foundation volunteers at Rest Stop 2, where they helped hydrate and feed cyclists in need of a break.
Vanderkitten cyclist Maura Kinsella racing along.
Canary Founder Don Listwin with son Hunter gave riders words of encouragement before the race.
What Will Cancer Early Detection Look Like?
September 18, 2012
Co- authored by Abbie Lieberman.
Imagine the year is 2030. Jane Doe has been feeling under the weather and is experiencing unfamiliar stomach pain. Her doctor sends her a portable, at-home screening kit that can test for multiple conditions including a variety of cancers. She takes a picture of the results using her smart device and sends them off to her doctor. A day later in the clinic, her doctor informs her that she has the earliest stages of ovarian cancer detectable. In this future time, Jane’s cancer cells are removed quickly and she is out of danger. In such a world, cancer is found early and is eliminated or reduced to a chronic illness, rarely being a fatal disease. Jane is closely monitored from this time forward and she goes on to live a long and happy life.
When cancer early detection tools become a reality, cancer screenings will change drastically and so will the impact of this disease on human life. Cancer could be re-categorized to become a condition or a disease swiftly dealt with, with fewer side effects or damage to the body. However, at-home tests to detect cancer early could be a long way off in the future. Is there something we can believe in without waiting for the Jane Doe scenario to come about?
In the more near-term, Canary researchers foresee important steps becoming practiced in our lifetime. A patient will most likely go into a doctor’s office, and get an extensive panel of blood work done at an annual exam. If the results are positive, an imaging test will be conducted to determine exactly where the cancer cells are. We already know this truth: when found early, a tumor can be removed or treated before it spreads. The patient’s survival rate increases to 90% (generalized) compared to the 10% survival rate when found late (today’s norm). More »
Nicole Urban on Canary’s Ovarian Cancer Research Program
September 6, 2012
Nicole Urban, Ovarian Cancer Team Co-leader at the Canary Center and investigator at the Fred Hutchinson Cancer Research Center, provides viewers with an overview and the goals for Canary’s Ovarian Cancer Research Program. She also explains how working on collaborative research initiatives with Canary Foundation helps push her research to the next level.
Canary Challenge Update: Did You Know…?
August 31, 2012
Cyclists who have been training (hopefully!) and fundraising for weeks will descend upon the campus of VMware in Palo Also to ride in the Canary Challenge 2012 in September. The Canary Challenge is one of the most picturesque rides on the west coast—going from the foothills of Palo Alto & Woodside, to Pescadero, out to the Pacific Ocean.
The Canary Challenge benefits the Stanford Cancer Institute (SCI) and 100% of funds raised will be donated to the SCI for cancer research and innovative clinical programs.
The one-day ride is a fully supported ride that includes great food, generous amenities, stocked rest stops, SAG vehicles, medical support, spirited festivities, and wine & beer garden, and a community of riders who have been touched one way or another by cancer. Learn more about the Canary Challenge on our website.
Some interesting facts about the Canary Challenge: Did You Know . . ?
- The male to female rider ratio this year is 2: 1. In 2011, it was 3:1. What an increase in women riders!
- The two biggest teams are Canary Chicks with 27 riders (4 male riders!) and Team Lauren (in support of LPCH) with 24 riders.
- A bake sale can raise a lot of money! Avaya The Power of WeTM team held a bake sale at their corporate headquarters during the lunch hour and raised $1,343 in 3 hours. More »
